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Research
Neuroscience, neuroregeneration, CRISPR/Cas9

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Project Management and Dissemination
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Establishment and characterization of the 3D in vitro SCI model and testing the CRISPR / Cas9 gRNA loaded exosome functionalized piezoelectric fibers

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Production and characterization of piezoelectric of PVDF/ cellulose acetate fibers,Functionalization of PVDF/cellulose acetate fibers with CRISPR/Cas9 and exosomes
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In silico modelling of gRNA/exosome loading/release

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Determination of target genes by bioinformatics and design and production of the gRNA sequences of the determined genes by CRISPR / Cas9

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Testing the functionalized fiber conduits in in vivo rat SCI model

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​Preparation and characterization of CRISPR/Cas9 gRNA carrying exosomes

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